Here's a small tip;
When making a spell macro you are able to add a modifier which requires you to hold down shift.
These are untested. vCode:/cast [target=target,modifier:shift] Mana Burn
This might also work with alt and ctrl.
Code:/cast [target=target,modifier:alt] Mana BurnMaybe hold down shift+ctrl?Code:/cast [target=target,modifier:ctrl] Mana Burn
Code:/cast [target=target,modifier:shift,modifier:ctrl] Mana Burn