I am currently looking into how much profit I can make with Transmute Mastery and decided to craft a spreadsheet that would allow myself and others to see profits for meta gems, titanium bars, and the epic gems.
Once you download the spreadsheet just open it with excel and then input values for all the the items labeled with a dark gray box. Once you have entered the necessary values new values will appear in the green boxes which are your totals and profits. Everything is clearly labeled and should be easy to follow. It may seem like a hassle at first having to keep updating the AH values every time you want to recalculate profits but in the end it's worth it.
Remember that all profit values are based on a output of 1 which is not always the case if you are transmute spec and can proc. The values shown are bare minimum profits
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* New download link so you should be able to get it now*