The file types are just if you can't get one of them to work. The .pmc is for the macro editor if you want to run it straight from that or compile it to an exe yourself. The ahk and exe are alternatives. Make sure you install autohotkey if they aren't working and are using f4 to start the macro, f8 to stop, f12 to pause and resume. Would be very hard for multiple instances as you would need to code it for multiple pixel detection regions and the mouse coordinates would have to choose which window.