Lots of stupid people in this thread who didn't read the guide. If nothing is happening, plug your mouse into another USB port. Do a mouse driver test. If nothing still happens, well now you know why.
The actual pixelbot is amazing. However the flickshot doesn't work after fiddling with the speed several times it just doesn't aim right. That's a small thing to me though. You don't really need it. Just use the aimbot.