Just a theory but here it goes....
ok so i found out that caltrops with the jagged spike rune triggers life on hit. Caltrops does damage every second and you can have 5 at once. With 800life life on hit thats 4000 life a sec per enemy you hit with 5 caltrops. Toss in chakram - shuriken cloud thats 4800k life per hit, possibly higher by using a primary aoe skill aswell. So my idea is stacking res and vit and having at least 1k life on hit to not go down in inferno. There may need to be sum kitting when prep is on cd tho.
What do you guys think?