Originally Posted by
StarI3lade
Let me clarify this:
Abilities such as Cleave, Whirlwind, etc will still make you take damage. That is because these abilities "physically" hit the the Sister of Pain even though she is not targetted.
However, abilities such as Blade Fury and Sweeping Strikes do not "physically" target the Sister of Pain when dealing damage to her thus you won't take the 2500 through use of such abilities.
This was tested last night in BT by our DPS Warrior using Sweeping Strikes and by a Rogue using Blade Fury and neither took damage.