one of the most annoying rumbles to beat on the Brawler's Guild is the Stranglethorn Run, which makes you naked and 1-shottable and you have to survive for 2 minutes avoiding a lot of beasts that spawn.
but the naked effect is just visual and you still have your azerite traits. if you have a piece of gear with Resounding Protection, your HP will be reduced but you`ll still have a 15k shield that makes you invincible to the beasts attacks. just stay still until the brawl ends