So i found a buff that i think is going to be great for when your attempting new bosses in cataclysm or current content before a pull. This buff gives you 100% increased dmg but like the title says there's a catch and that is that you also take 100% dmg. The Duration of the buff is 1min(60sec). The name of the quest is Waste of Thyme in Azshara.
If your a lock you can use soul shatter to help lose all that threat you gained.