Note: To look at the new titles being added in WoTLK check out MMO Chaampion (front page)
It's pretty simple really...
1. Find an extremely low-population server. (Warcraft Census - is good for this)
2. A few days before the release of WoTLK (not the content patch) transfer the character(s) you want the titles on to said low-population server.
3. Achieve titles with little competition.
4. Transfer back.
So, is a unique title that one person per server can get worth $50+? I'd say so. Think of it this way, if you could have spent $50 to get the black bug mount, would you have?