A brief introduction to these unique items that can be used by all classes. Powerful but hard to get. It doesn't make much sense to me personally.
Andariel's Visage
Ancestral Unique Helm. 820 Item Power. 1025 Armor.
+ Life steals/all stats/attack speed/poison resistance.
The Unique Affix offers a 15 - 20% chance to trigger a poison nova when you trigger a Lucky Hit.
Razorplate
Ancestral Unique Chest Armor. 725 Item Power. 1269 Armor.
Only one Unique Affix, no common affixes. Gain 6,293 – 8,653 Thorns.
Best for classes with a lot of health or high defense, such as Barbarians and Druids.
Frostburn
Sacred Unique Gloves. 725 Item Power. 363 Armor.
+Freeze Duration/Cold Damage/Critical Strike Chance
You will have up to a 5% chance to recover 7-14% of the primary resource and a 15-25% chance to freeze enemies for 2 seconds on a lucky hit.
Fists of Fate
Ancestral Unique Gloves. 725 Item Power. 363 Armor.
A bunch of Lucky Hit bonuses, 9.5-16.5% chance to daze, 5% chance to restore 7-14% primary resource, 5% chance to heal 367-661 life, 9.5-16.5% chance to immobilize on a lucky hit, and your attacks randomly deal 1-300% normal damage.
Melted Heart of Selig
Ancestral Unique Amulet. 820 Item Power.
+ Resistance to All Elements/Resource Generation/Core Skill Damage/All Stats/Damage while Healthy
Unique Affix offers+30% maximum resource and drains 8 - 3 resources for every 1% of life you would have lost instead when you take damage.
Harlequin Crest
Ancestral Unique Helm. 820 Item Power. 1,025 Armor.
+ Maximum Life/Resource Generation/All Stats/Cooldown Reduction
Unique Affix offers 10-20% damage reduction and +4 Ranks to all Skills.
Mother's Embrace
Sacred Unique Ring. 725 Item Power
+Shadow Resistance/Fire Resistance/Overpower Damage/Lucky Hit Chance/All Stats/Critical Strike Damage
Unique Affix offers 20 - 40% of the cost of resources if a Core Skill hits 5 or more enemies.
Penitent Greaves
Sacred Unique Boots. 725 Item Power. 363 Armor.
Evade Grants+50% Movement Speed for 1 second
+Slow Duration Reduction/Movement Speed/Cold Resistance/Crowd Control Duration
Unique Affix lets you leave a trail of frost that can chill enemies and offers 7-10% increased damage to chilled enemies.
Ring of the Starless Skies
Ancestral Unique Ring. 820 Item Power
+Cold Resistance/Fire Resistance/Critical Strike Chance/Lucky Hit Chance/Core Skill Damage/Critical Strike Damage
Unique Affix reduces the resource cost of your next Core Skill by 8-12% up to 40% with consecutive Core Skill cast.