INFERNO ONLY
In this guide I will show you what I use to farm Iskatu on the first part of Act IV for easy gold and items.
*NOTICE*
This may require some decent gear I have around 54k DPS as full glass cannon and I can do this fine.
All my stats:
Recommended Talents: Wizard - Game Guide - Diablo III
Temporal Flux, Glass Cannon, Archon, Magic Weapon, and Familiar are not optional but you can do without the other talents.
Energy Armor with Pinpoint Barrier rune is nice for the extra crit but is not necessary.
Archon is the key to this because you gain time as you kill the little spawns that he makes and the right click does massive damage. You will really want to be pumping out the damage because this guy can easily 1 shot you on Inferno so you will always want to be on him so be sure to be looking at your map to see where you should be pointing without actually seeing him.
Start out by going to the start of Act IV
Go talk to Tyreal and go through the portal and walk up and go into this corner of the gate.
I like to start out with my Hydra out and then go into archon and hold down right click and aim towards the middle of the room because that is where the boss will spawn. At around 60% he will teleport back into the middle.
The spoils
You also get around 1.6K gold for completing the quest after killing him. I have gotten quite a few nice pieces including a 1.2K DPS Crossbow.
This can be easily done in a minute or less depending on your gear.
If you are having troubles with this you should spam your 1 in Archon. Another way you could up your damage is by putting on the Arcane Dynamo passive and using Electrocute with Chain Lightning to build stacks quickly then use Archon at 5 stacks and you will have 75% increased damage. Besides that all I can recommend is better gear.