I discovered this having had a bot run through all servers for 24 hours, farming "Hozen Peace Pipe".
I gathered something like 43 Pipes, along with shitloads of random blues.
So i clicked it, and noticed a small lag when clicking the item, and it going on cd/giving you rep.
So what i did was to wait 7 days for the cooldown to wear up, bind the pipe to all my actionbars, then used the prospector program to click with an interval of 1 ms.
to my amusement, it managed to click 31 pipes before dcing me.
logged back on, and had gained around 39k reputation (used the guildbanner+lvl 25 guild)
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My wow stats before runninig this:
81 fps, max graphics and somewhat between 400-700 ms.
I also macroed it, to be inside a macro the most times it could possibly be done.
Also, i used a lvl 90 Hunter, Pandaren Horde.